Immunomodulators for Eczema
- Saesha Loonker
- Jan 1, 2024
- 2 min read
Updated: Jun 19, 2024

In this blog post, we'll delve into two promising immunosuppressants, Cibinqo and Rinvoq, exploring how they work and their potential benefits for eczema patients.
Immunomodulators are medications that work by modulating the immune system, reducing inflammation and preventing the body's immune response from attacking healthy tissues. We have already discussed about the potential side effect of the long-term use steroids . This has led to the development of alternative treatments like Cibinqo and Rinvoq.
Cibinqo (abrocitinib): Cibinqo is a novel Janus kinase (JAK) inhibitor approved by the U.S. Food and Drug Administration (FDA) for the treatment of moderate to severe eczema in adults and adolescents aged 12 years and older. It works by blocking specific enzymes involved in the inflammatory process, thereby reducing symptoms of eczema such as itching, redness, and skin lesions. Clinical trials have shown promising results, with many patients experiencing significant improvements in their symptoms.
Rinvoq (upadacitinib): Rinvoq is another JAK inhibitor that has shown efficacy in the treatment of eczema. While it is not yet approved specifically for eczema, it has demonstrated positive outcomes in clinical trials for other inflammatory conditions such as rheumatoid arthritis. Like Cibinqo, Rinvoq works by targeting the JAK-STAT pathway, interrupting the inflammatory cascade and providing relief from eczema symptoms.
Both Cibinqo and Rinvoq offer potential benefits for eczema patients, including improved symptom control, reduced inflammation, and enhanced quality of life. I am pretty sure patients like me who are scared of injecting themselves every week, an oral pill is a much better option. However, it's essential to weigh the benefits against potential risks and side effects, which can include increased susceptibility to infections and gastrointestinal issues.
Cibinqo and Rinvoq, for sure are a promising additions to the treatment options for eczema. It i important to stay informed about these innovative therapies, so that we can take proactive steps towards managing this condition and improving our quality of life.
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